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Early Fluid Resuscitation With Balanced HES 130/0.4 [6%] in Severe Burn Injury

2014-07-23 21:11:49 | BioPortfolio

Summary

RCT colloids versus cristalloids only in severe burn victims.

- Trial with medicinal product

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Burns

Intervention

Fluid resuscitation, HES 130/0.5 (6%), Voluven balanced

Location

Surgical ICU
Zurich
Switzerland
8091

Status

Recruiting

Source

University of Zurich

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:11:49-0400

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Medical and Biotech [MESH] Definitions

Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Accidental injuries caused by brief high-voltage electrical discharges during thunderstorms. Cardiopulmonary arrest, coma and other neurologic symptoms, myocardial necrosis, and dermal burns are common. Prompt treatment of the acute sequelae, including cardiopulmonary resuscitation, is indicated for survival.

Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include, but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Burns of the respiratory tract caused by heat or inhaled chemicals.

Burns caused by contact with or exposure to CAUSTICS or strong ACIDS.

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Surgery is a technology consisting of a physical intervention on tissues. All forms of surgery are considered invasive procedures; so-called "noninvasive surgery" usually refers to an excision that does not penetrate the structure being exci...


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