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Efficacy and Safety of Specific Immunotherapy With CLUSTOID Grass Pollen

2014-07-23 21:11:49 | BioPortfolio

Summary

The objective of this study is to assess the efficacy and safety of cluster immunotherapy with highly polymerized allergen extracts.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Allergic Rhinitis

Intervention

Subcutaneous injections with highly polymerized allergen extract, Subcutaneous injection with placebo

Location

Zentrum für Rhinologie und Allergologie
Wiesbaden
Germany

Status

Active, not recruiting

Source

Roxall Medizin

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:11:49-0400

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Medical and Biotech [MESH] Definitions

The uptake of substances via the SUBCUTANEOUS TISSUE.

Presence of air or gas in the subcutaneous tissues of the body.

Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.

The application of medicine, vitamins, extracts, or other bioactive substances for a localized effect via multiple subcutaneous injections or perfusion of substances into the various layers of the skin below the EPIDERMIS.

The measurement of subcutaneous fat located directly beneath the skin by grasping a fold of skin and subcutaneous fat between the thumb and forefinger and pulling it away from the underlying muscle tissue. The thickness of the double layer of skin and subcutaneous tissue is then read with a caliper. The five most frequently measured sites are the upper arm, below the scapula, above the hip bone, the abdomen, and the thigh. Its application is the determination of relative fatness, of changes in physical conditioning programs, and of the percentage of body fat in desirable body weight. (From McArdle, et al., Exercise Physiology, 2d ed, p496-8)

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The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...


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