Metagenomic Analysis of Gut Microbiome in Korean Patients With Ulcerative Colitis
Summary
The researchers will investigate gut microbiome in Korean patients with ulcerative colitis and normal control subjects using metagenomic analysis to elucidate the significant difference between two groups This study will help to understand the association between gut microbiome and inflammatory bowel disease.
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Conditions
Intervention
Colonoscopy biopsy, stool collection, colonoscopy biopsy, stool collection
Location
Seoul National University Hospital
Seoul
Korea, Republic of
110-744
Status
Recruiting
Source
Seoul National University Hospital
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01010815
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-08-27T03:18:04-0400
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Medical and Biotech [MESH] Definitions
Colitis, Collagenous
A subtype of MICROSCOPIC COLITIS, characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. Microscopic examination of biopsy samples taken from the COLON show larger-than-normal band of subepithelial COLLAGEN.
Colitis, Lymphocytic
A subtype of MICROSCOPIC COLITIS, characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. Microscopic examination of biopsy samples taken from the COLON show infiltration of LYMPHOCYTES in the superficial EPITHELIUM and the underlying connective tissue (lamina propria).
Colitis, Microscopic
A condition characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. This syndrome was first described in 1980 by Read and associates. Subtypes include COLLAGENOUS COLITIS and LYMPHOCYTIC COLITIS. Both have similar clinical symptoms and are distinguishable only by histology.
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