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Study to Evaluate the Efficacy and Safety of GSK239512 in Schizophrenia

2014-08-27 03:18:09 | BioPortfolio

Summary

This study aims to evaluate the cognitive enhancing effects and tolerability of GSK239512 compared to placebo in patients with schizophrenia

Description

This is a 7-week, Phase II, multi-centre, randomised, double-blind, placebo-controlled, parallel group design study in male and female subjects with schizophrenia who are stabilised on antipsychotic medication. Subjects will undergo an open-label, single-dose d-amphetamine therapeutic challenge in a hospital setting before being randomised to receive either GSK239512 or placebo for 7 weeks. They will undergo weekly review of safety, tolerability and cognitive performance measures.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Schizophrenia

Intervention

GSK239512, Placebo, d-amphetamine

Location

GSK Investigational Site
Los Angeles
California
United States
90073

Status

Recruiting

Source

GlaxoSmithKline

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:09-0400

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