Prospective Randomized Comparison of Transurethral Resection by Mean of White Light and Narrow Band Imaging

2014-08-27 03:18:20 | BioPortfolio


To date, fluorescence and narrow band imaging cystoscopy have been tested in many prospective within patient trials but only as an "add on" procedure. This results in a bias that does not allow to determine the real impact of such innovative technologies on bladder cancer management. Hereby we propose the first prospective randomized trial which compares narrow band imaging trans urethral resection as a stand alone procedure versus white light transurethral resection. The primary end point is to assess the recurrence rate of bladder cancer lesions with each treatment modality. The study is designed to disclose an inferior recurrence rate (estimated 10%) in the group treated by narrow band imaging transurethral resection respect to the control group, treated by standard transurethral resection.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Non Muscle Invasive Bladder Cancer


Narrow band imaging transurethral resection, Standard transurethral resection


National Institute for Cancer Research (IST)




National Institute for Cancer Research, Italy

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:18:20-0400

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Medical and Biotech [MESH] Definitions

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