Differential Metabolic Effects of Fenofibrate and Fatty Acid
Summary
The investigators hypothesize that fenofibrate and fatty acid may have different metabolic effects in hypertriglyceridemic patients
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Conditions
Location
Gil Medical Center
Incheon
Korea, Republic of
405-760
Status
Recruiting
Source
Gachon University Gil Medical Center
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01003847
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-08-27T03:18:21-0400
Clinical Trials
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Pharmacogenetics of Hypertriglyceridemia in Hispanics
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The purpose of the study is to compare the efficacy and tolerability of fenofibrate 160 mg and niacin 1500 mg in patients with hypertriglyceridemia and low HDL-cholesterol. The primary end...
Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia
The goal of this study is to evaluate the effects of replacing some refined starches and added sugars with a combination of egg protein and unsaturated fatty acids on markers of cardiometa...
PubMed Articles
Hypertriglyceridemia: A review of the evidence.
Elevated triglycerides are independently associated with increased atherosclerotic cardiovascular disease risk. Hypertriglyceridemia is often a polygenic condition that can be affected by a myriad of ...
Hypertriglyceridemia thalassemia syndrome.
Hypertriglyceridemia thalassemia syndrome is a rare entity with an unknown pathogenetic link.
Acute pancreatitis secondary to oral contraceptive-induced hypertriglyceridemia: a case report.
Hypertriglyceridemia is the third most common cause of acute pancreatitis. Among the causes that lead to secondary hypertriglyceridemia, the use of contraceptive agents is the main reason to be assess...
Hypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis. In patients with severe HTG (TG level>1000 mg/dL), it may be beneficial to immediately lower the levels of triglyceride...
There is evidence that increasing severity of hypertriglyceridemia increases the risk of acute pancreatitis. There is a debate about superiority of treatment methods and previous works have specifical...
Medical and Biotech [MESH] Definitions
Hypertriglyceridemia
A condition of elevated levels of TRIGLYCERIDES in the blood.
Clofibrate
A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Lipodystrophy, Congenital Generalized
Congenital disorders, usually autosomal recessive, characterized by severe generalized lack of ADIPOSE TISSUE, extreme INSULIN RESISTANCE, and HYPERTRIGLYCERIDEMIA.
Hyperlipoproteinemia Type Iv
A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits.
