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In Vivo Evaluation of the Physiological Effects of Arabinoxylan-oligosaccharides (AXOS) in Healthy Subjects (Juniors)

2014-08-27 03:18:26 | BioPortfolio

Summary

The investigational product used in this study is a soft drink containing an arabinoxylan-oligosaccharide (AXOS) preparation extracted from wheat bran (hereafter called Wheat Bran Extract, WBE).

The objective of this study is to analyze the effect of the intake of WBE on various parameters of gastrointestinal health in children (8-12 yrs). Additionally, safety was analyzed using treatment emergent Adverse Events (AEs).

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care

Conditions

Gastrointestinal Health

Intervention

Wheat Bran Extract, placebo

Location

Department of Gastrointestinal Research, Laboratory Digestion and Absorption
Leuven
Belgium
3000

Status

Completed

Source

Fugeia NV

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:26-0400

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In Vivo Evaluation of the Physiological Effects of Arabinoxylan-oligosaccharides (AXOS) in Healthy Subjects (Adults)

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PubMed Articles [17216 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

OIL extracted from the hard outer brown layer of rice bran after the husk has been removed.

Allergic reaction to wheat that is triggered by the immune system.

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A plant genus of the family POACEAE that is the source of wheat grain. A hybrid with rye (SECALE CEREALE) is called TRITICALE. The seed is ground into FLOUR and used to make BREAD, and is the source of WHEAT GERM AGGLUTININS.

Lectins purified from the germinating seeds of common wheat (Triticum vulgare); these bind to certain carbohydrate moieties on cell surface glycoproteins and are used to identify certain cell populations and inhibit or promote some immunological or physiological activities. There are at least two isoforms of this lectin.

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