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Study to Determine the Effects of Nebivolol and Hydrochlorothiazide in African Americans With Hypertension

2014-08-27 03:18:28 | BioPortfolio

Summary

The main purpose of this study is to evaluate the effects of Nebivolol and Hydrochlorothiazide on blood pressure in African Americans with high blood pressure.

Description

Many blood pressure medications are not effective in African American men and women. The two lower chambers of the heart contract to pump blood to the body. The lower chambers have to relax so they can refill with blood to pump out again. Many patients with high blood pressure have stiffness in the lower chambers which prevents the heart from relaxing so it can properly fill with blood. Some patients with the stiffness in the lower chambers of the heart will develop heart failure.

The study is to test whether or not Nebivolol (Bystolic)and a diuretic Hydrochlorothiazide (HCTZ) will help the heart relax so the heart can properly fill and prevent stiffness of the lower heart chambers.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Conditions

Hypertension

Intervention

Nebivolol, Hydrochlorothiazide

Location

Atlanta Vascular Research Foundation
Tucker
Georgia
United States
30084

Status

Recruiting

Source

InVasc Therapeutics, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:28-0400

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PubMed Articles [1989 Associated PubMed Articles listed on BioPortfolio]

The current position of hydrochlorothiazide among thiazide and thiazide-like diuretics.

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Medical and Biotech [MESH] Definitions

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Hypertension due to RENAL ARTERY OBSTRUCTION or compression.

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