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A Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors

2014-08-27 03:18:32 | BioPortfolio

Summary

The primary objective of this study is to determine the maximum tolerated dose (MTD) or recommended phase II doses of sapacitabine and seliciclib administered sequentially. The secondary objectives are to evaluate antitumor activity of this sequential treatment and to explore the pharmacodynamic effect of this treatment in skin and peripheral blood mononuclear cells.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Advanced Solid Tumors

Intervention

sapacitabine and seliciclib

Location

Dana Farber Cancer Institute
Boston
Massachusetts
United States
02115

Status

Recruiting

Source

Cyclacel Pharmaceuticals, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:32-0400

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