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Trichomoniasis: Genotype and Phenotype Correlations in African American Women

2014-07-24 14:11:10 | BioPortfolio

Summary

The hypothesis to be tested in this trial is that the different epidemiologic (including racial differences) and phenotypic manifestations exhibited by Trichomonas clinical isolates during infection are correlated with their genotypic strain classification. Two specific aims are proposed to test that hypothesis. Specific aim 1. Assess the significance of genotypic or phenotypic differences in the Trichomonas strains among African American women by HIV status. Specific aim 2. Determine the significance of genotypic or phenotypic differences in the Trichomonas strains circulating among women from two different racial groups, African American women and Caucasian women. The overall goals of these specific aims are to identify racial differences in the genotypic and phenotypic characteristics of Trichomonas strains, and to develop the ability to identify and classify Trichomonas infections in order to prioritize treatment and epidemiologic follow-up of individuals infected with isolates associated with adverse clinical outcomes (HIV transmission or acquisition, pregnancy complications, virulence, or drug resistance).

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Conditions

Trichomonas Infections

Location

Crossroads Clinic
Jackson
Mississippi
United States
39213

Status

Recruiting

Source

University of Mississippi Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:11:10-0400

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Medical and Biotech [MESH] Definitions

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