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Efficacy and Safety of Lornoxicam in Patients With Acute Coronary Syndrome

2014-08-27 03:18:34 | BioPortfolio

Summary

The purpose of this study is to determine whether nonsteroidal antiinflammatory drug lornoxicam in combination with low dose aspirin (100mg/day) is effective and safe in patients with Acute Coronary Syndrome without persistent ST-segment elevation.

Description

Nonsteroidal Antiinflammatory drugs (NSAIDs) are the most frequently prescribed drugs in the world. There are a lot of controversial information published during recent years about NSAID cardiosafety. It is still unclear do NSAIDs develop cardioprotective or cardiotoxic effects in acute and chronic heart disease patients. Aim of the study was to investigate safety and efficacy of Lornoxicam, nonselective COX-inhibitor, in patients with acute coronary syndrome without ST-segment elevation (NSTEACS) and to evaluate the influence of Lornoxicam on C-reactive protein (CRP) and IL-6, IL-10 levels.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Acute Coronary Syndrome

Intervention

Lornoxicam

Location

Central Clinical Hospital of Presidential Department Of Russian Federation
Moscow
Russian Federation

Status

Completed

Source

Central Clinical Hospital of the Presidential Administration of the Russian Federation

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:34-0400

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