Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients

2014-07-23 21:12:26 | BioPortfolio


The rationales of a clinical trial comparing intralesional antimonial therapy versus wound care management in patients with old world cutaneous leishmaniasis (OWCL) are the following:

1. The effectiveness of the current mainstay treatment with intralesional antimonials for CL is subject to discussion, especially in L. major lesions which are predominant in Northern Afghanistan

2. The importance of wound care management in patients with OWCL has been emphasized by Gonzalez et al. (2008) and its efficacy is confirmed in the Kabul trial with L. tropica patients.

Parallel to the clinical effectiveness the trial investigates the cost-effectiveness and -utility of the treatment options under study.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Wound Healing


Electro-thermo-coagulation, Sodium Stibogluconate, DAC N-055


Leishmaniasis and Malaria Center




Waisenmedizin e. V. Promoting Access to Essential Medicine

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:12:26-0400

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Medical and Biotech [MESH] Definitions

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

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