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Efficacy and Tolerability of Intranasal Fentanyl Spray for the Treatment of Breakthrough Pain in Cancer Patients Older Than 18 Years

2014-08-27 03:18:41 | BioPortfolio

Summary

The aim of the study is to evaluate the safety and efficacy of intranasal fentanyl spray in cancer patients over four weeks, especially during cancer-related breakthrough pain (BTP) attacks. The fentanyl spray will be applied into the nose by a metered-spray device. The study will provide further data on pharmacoeconomic efficiency of intranasal fentanyl spray.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Breakthrough Pain

Intervention

Instanyl (Intranasal Fentanyl)

Location

Nycomed Deutschland GmbH
Aachen
Germany
52074

Status

Recruiting

Source

Nycomed

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:41-0400

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Medical and Biotech [MESH] Definitions

Acute pain that comes on rapidly despite the use of pain medication.

A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)

A type of pain that is perceived in an area away from the site where the pain arises, such as facial pain caused by lesion of the VAGUS NERVE, or throat problem generating referred pain in the ear.

The administration of drugs through the nasal passage.

Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

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