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Double and Single Intrauterine Insemination In Controlled Ovarian Stimulation (COH) Cycles With Multifollicular Development

2014-07-23 21:12:29 | BioPortfolio

Summary

Our hypothesis is double insemination will improve pregnancy rates in coh cycles with more than one dominant follicles (>16mm).

Description

Metaanalysis for the effects of double IUI demonstrates that effects of this procedure is not different from single IUI. It is known that nearly 25% of coh cycles is evident by monofollicular development.For this reason it is possible that this monofollicular cycles in the studies could decrease the effects of double IUI.

Inclusion criteria:

1. Patients with unexplained infertility or mild male factor infertility whom admitted to the COH+IUI programme in our infertility unit.

2. Female age <37 years old.

3. Baseline FSH <12 mIU/L

4. Total antral follicle count>6

5. During the first three cycles of COH+IUI

6. Minimum 2 follicles >16 mm at the day of HCG.

Primary outcome:

Ongoing pregnancy rates

Secondary outcomes:

The effects of different coh regimens (CC,FSH,CC+FSH)on the outcomes.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Infertility

Intervention

Intrauterine insemination (single), Double intrauterine insemination

Location

Baskent University Medical Faculty Obstetric and Gynecelogy Department, Infertility and IVF unit
Adana
Turkey
01120

Status

Completed

Source

Baskent University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:12:29-0400

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