Study of Cytokines Serum Levels in Chronic Low Back Pain

2014-08-27 03:18:48 | BioPortfolio


The purpose of this study is to:

- evaluate if there is an association between elevated levels of cytokines and chronic pain due to herniated disk disease

- measured cytokines levels in chronic low back pain and in healthy subjects.


23 patients with at least three months of back pain due to herniated disk disease were selected Diagnosis was confirmed by magnetic resonance imaging (MRI) or computerized tomography (CT) imaging of the spine for all patients. In addition, pain severity had to be ³ 5 points on the Numerical Rating Scale (NRS) ranging from zero (no pain) to 10 (worst imaginable pain).

The exclusion criteria were defined as one or more of the following: psychiatric disorders, systemic or inflammatory disease, history of allergy, presence of motor deficits, history of blood dyscrasia, pregnancy, active infection, tumor, use of analgesic drugs in the week before or inability to come to the hospital for evaluation.

Study Design

Control: Active Control, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Health Services Research




blood collect


Universidade Federal da Bahia




Federal University of São Paulo

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:18:48-0400

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