Study of the Efficacy of Sharp Debridement for the Management of Chronic Wounds
Summary
Standard care of care and up to twelve (12) weekly debridements. Subjects randomized into the weekly debridement group will receive up to twelve (12) debridement during the twelve (12) weeks of the study. There will be two (2) subject groups in the study. Subjects will be randomized into either the monthly debridement group or the weekly debridement group.
Description
The primary objective of this study is to evaluate subjects enrolled and randomized to the weekly sharp debridement group.
The major secondary objectives are incidence of complete wound closure at Week 12, rate of healing, ulcer recurrence, wound characteristics, and microbiologic information.
Study Design
Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Conditions
Wounds
Intervention
debridement
Status
Active, not recruiting
Source
Southwest Regional Wound Care Center
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00990522
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-07-23T21:12:35-0400
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Medical and Biotech [MESH] Definitions
Head Injuries, Penetrating
Head injuries which feature compromise of the skull and dura mater. These may result from gunshot wounds (WOUNDS, GUNSHOT), stab wounds (WOUNDS, STAB), and other forms of trauma.
Wounds, Stab
Penetrating wounds caused by a pointed object.
Wounds, Penetrating
Wounds caused by objects penetrating the skin.
Pfiesteria Piscicida
A dinoflagellate with a life cycle that includes numerous flagellated, amoeboid, and encysted stages. Both the flagellated and amoeboid forms produce toxins which cause open wounds on fish. Pfiesteria piscicida feeds on tissue sloughed from these wounds, as well as on bacteria and algae. It is found in Atlantic estuaries of the United States.
Debridement
The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)
