Effect of Aerobic Training on Asthmatic Patients

2014-08-27 03:18:53 | BioPortfolio


The investigators hypothesize that aerobic training can reduce anxiety, depression and airway inflammation and those benefits may be related to changes in autonomic system.


One-hundred patients with moderate or severe persistent asthma, age ranging from 20 to 50 years-old recruited after a medical consultation. Asthma diagnosis based on GINA1 and patients were under medical treatment for at least 6-months and considered clinically stable (no crises and changes in medication for at least 30 days). Patients diagnosed with cardiovascular, pulmonary or musculoskeletal diseases impairing exercise training were excluded.

Experimental Design: Patients were studied between 2 medical consultation to avoid changes in medication during the study and patients were randomized (by drawing lots) into either Control or Training groups. CG was submitted to a 4-hour educational program and a breathing exercise program and TG was submitted to the same CG procedures plus an aerobic training program individually based on VO2max. Before and after the intervention, patients performed pulmonary function test and cardiopulmonary exercise testing and as well as fulfilled questionnaires to quantify asthma specific HRQL and anxiety and depression levels. Asthma daily symptoms were evaluated monthly.

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment




Aerobic training


Clinical Hospital, School of Medicine, University of São Paulo
São Paulo




University of Sao Paulo General Hospital

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:18:53-0400

Clinical Trials [2045 Associated Clinical Trials listed on BioPortfolio]

Healthy Eating Aerobic and Resistance Training in Youth (HEARTY) Trial

The purpose of this study is to evaluate the effects of resistance training, aerobic training, and combined aerobic and resistance training on percent body fat, measured using Magnetic Res...

Effects of Different Mode of Exercise Training on Type 2 Diabetes

Randomized study on the comparison between aerobic training versus progressive resistance training over a 2 months period for older adults with type 2 diabetes. The hypothesis is that prog...

Aerobic, Resistance, Inspiratory Training Outcomes in Heart Failure

This study investigates the effects of aerobic, resistance, inspiratory training modalities outcomes in functional capacity and quality of life of heart failure (HF) patients, aiming for t...

Effects of Aerobic Training and Inspiratory Muscle Training in Patients During Hematopoietic Stem Cell Transplantation

The hospitalization for hematopoietic stem cell transplantation (HSCT) impairs the physical functioning and functional capacity, but aerobic physical training and, more recently, inspirato...

Muscle Metabolic Function in Older Adults With Different Vitamin D Status Before and After Exercise

This is a small pilot aerobic training trial designed to examine differences between normal-high and low vitamin D levels and 7-days of aerobic training on local VO2 measured by non-invasi...

PubMed Articles [4990 Associated PubMed Articles listed on BioPortfolio]

The efficacy of aerobic exercise and resistance training as transdiagnostic interventions for anxiety-related disorders and constructs: A randomized controlled trial.

Evidence supports exercise as an intervention for many mental health concerns; however, randomized controlled investigations of the efficacy of different exercise modalities and predictors of change a...

Aerobic Interval vs. Continuous Training in Patients with Coronary Artery Disease or Heart Failure: An Updated Systematic Review and Meta-Analysis with a Focus on Secondary Outcomes.

In a previous meta-analysis including nine trials comparing aerobic interval training with aerobic continuous training in patients with coronary artery disease, we found a significant difference in pe...

Aerobic exercise prior to task-specific training to improve poststroke motor function: A case series.

Aerobic exercise can improve upper limb motor function in both healthy and stroke populations. Research in animals after stroke has shown that aerobic exercise combined with forelimb motor training im...

Pilates and aerobic training improve levels of depression, anxiety and quality of life in overweight and obese individuals.

To compare the effects of Pilates and walking on quality of life, depression, and anxiety levels.

Increased Brain Glucose Uptake Following 12 Weeks of Aerobic High-intensity Interval Training in Young and Older Adults.

Aerobic exercise training can increase brain volume and blood flow, but the impact on brain metabolism is less known.

Medical and Biotech [MESH] Definitions

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. Some are also effective as anticonvulsants, muscle relaxants, or anesthesia adjuvants. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.

Financial support for training including both student stipends and loans and training grants to institutions.

Anxiety due to fantasized injuries to or loss of the genitals.

Anxiety related to the execution of a task. (Campbell's Psychiatric Dictionary, 9th ed.)

Persistent and disabling ANXIETY.

More From BioPortfolio on "Effect of Aerobic Training on Asthmatic Patients"

Quick Search


Relevant Topics

Psychiatry is the study of mental disorders and their diagnosis, management and prevention.  Conditions include schizophrenia, severe depression and panic disorders among others. There are pharmaceutical treatments as well as other therapies to help...

Public Health
Alternative Medicine Cleft Palate Complementary & Alternative Medicine Congenital Diseases Dentistry Ear Nose & Throat Food Safety Geriatrics Healthcare Hearing Medical Devices MRSA Muscular Dyst...

The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...

Searches Linking to this Trial