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Exposure Chamber Trial With Cat Immunotherapy

2014-08-27 03:18:57 | BioPortfolio

Summary

The main purpose of this trial is to investigate if any of three different doses of cat hair immunotherapy is safe for treatment of cat allergic patients.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Cat Allergy

Intervention

Specific allergen immunotherapy (placebo), Specific allergen immunotherapy, Specific allergen immunotherapy, Specific allergen immunotherapy

Location

Cetero Research
Mississauga
Ontario
Canada
L4W 1N2

Status

Recruiting

Source

ALK-Abelló A/S

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:57-0400

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PubMed Articles [17652 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

A quantitative form of intradermal testing for the relative allergenicity of a substance. It is used to determine the amount of an allergen that will be tolerated in ALLERGEN IMMUNOTHERAPY.

Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.

A plant genus of the family POACEAE that contains the Poa p Ia allergen and allergen C KBGP.

An active immunizing agent and a viable avirulent attenuated strain of Mycobacterium tuberculosis, var. bovis, which confers immunity to mycobacterial infections. It is used also in immunotherapy of neoplasms due to its stimulation of antibodies and non-specific immunity.

Form of passive immunization where previously sensitized immunologic agents (cells or serum) are transferred to non-immune recipients. When transfer of cells is used as a therapy for the treatment of neoplasms, it is called adoptive immunotherapy (IMMUNOTHERAPY, ADOPTIVE).

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