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Epidural Labor Analgesia and Infant Neurobehavior

2014-08-27 03:18:58 | BioPortfolio

Summary

Infant neurobehavior alteration is predictor of later intelligence development. Many factors would influence or are associated with infant neurobehavior, of which exist or appear during perinatal period. Neuraxial, especially epidural, analgesia to date is the most effective method in relieving labor pain. Although previous studies showed that opioid used in epidural analgesia for labor pain can affect newborn neurobehavior negatively in a dose-escalation associated manner, whether epidural analgesia itself would produce unpredictable effect on newborn neurobehavior is still unknown. Hereby the investigators designed this trial to investigate the hypothesis that epidural analgesia for labor pain control itself would not produce negative effect on infant neurobehavior.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Labor Pain

Intervention

Ropivacaine and sufentanil, Ropivacaine and sufentanil, Ropivacaine and sufentanil, Ropivacaine and sufentanil, Ropivacaine and sufentanil, Ropivacaine and sufentanil

Location

The Affiliated Nanjing Maternity and Child Health Care Hospital
Nanjing
Jiangsu
China
210004

Status

Recruiting

Source

Nanjing Medical University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:18:58-0400

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Medical and Biotech [MESH] Definitions

An opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent.

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