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Bendamustine as Second-Line Therapy in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

2014-07-24 14:11:25 | BioPortfolio

Summary

RATIONALE: Drugs used in chemotherapy, such as bendamustine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.

PURPOSE: This phase II trial is studying how well bendamustine works as second-line therapy in treating patients with relapsed or refractory small cell lung cancer.

Description

OBJECTIVES:

Primary

- To determine the time to progression in patients with relapsed or refractory small cell lung cancer treated with second-line bendamustine.

Secondary

- To determine the toxicity of this drug in these patients.

- To determine the response rate, progression-free survival, and overall survival of patients treated with this drug.

OUTLINE: This is a multicenter study.

Patients receive bendamustine IV over 1 hour on days 1 and 2. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 6 weeks.

Study Design

Masking: Open Label, Primary Purpose: Treatment

Conditions

Lung Cancer

Intervention

bendamustine hydrochloride

Location

Jones Clinic - Germantown
Germantown
Tennessee
United States
38138

Status

Recruiting

Source

National Cancer Institute (NCI)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:11:25-0400

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