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Study of Naltrexone for Methamphetamine Addiction

2014-08-27 03:19:04 | BioPortfolio

Summary

The purpose of this study is to determine whether methamphetamine-dependent individuals will use less methamphetamine when treated with naltrexone. The study will also investigate whether individuals with the mu opioid receptor gene variant A118G will use less methamphetamine than individuals without A118G.

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Methamphetamine Dependence

Intervention

Naltrexone

Location

Addiction & Pharmacology Research Laboratory
San Francisco
California
United States
94110

Status

Recruiting

Source

California Pacific Medical Center Research Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:04-0400

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PubMed Articles [1560 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.

Strong dependence, both physiological and emotional, upon morphine.

Strong physiological and emotional dependence on OPIUM.

Strong dependence, both physiological and emotional, upon heroin.

A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.

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