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Acute Comfort and Haze Profile of FID 114657

2010-07-15 17:00:00 | BioPortfolio

Summary

The purpose of this study is to describe the acute comfort and haze profile of FID 114657 in dry eye patients.

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Dry Eye

Intervention

FID 114657 ORB Preserved Ocular Emulsion, Soothe XP Lubricant Eye Drops

Location

Contact Alcon Call Center For Trial Locations
Fort Worth
Texas
United States
76134

Status

Completed

Source

Alcon Research

Results (where available)

View Results

Links

Published on BioPortfolio: 2010-07-15T17:00:00-0400

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An Evaluation of the Safety and Efficacy of FID 114657

The purpose of this study is to evaluate the safety and efficacy of FID 114657 in comparison to Soothe XP in a specified population of dry eye patients.

Evaluation of FID 114657 in Dry Eye Subjects

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Evaluation of FID 114657 on Tear Film Lipid Layer Thickness

To evaluate the effects of FID 114657 on the tear film lipid layer thickness of patients with dry eye.

Tear Film Break-Up Time Evaluation of FID 114657

To evaluate the effects of FID 114657 on tear film break-up time in dry eye patients.

Fluorophotometry Evaluation of Lubricant Eye Drops

The objective of this study is to evaluate the safety and efficacy of exaggerated use of Lubricant Eye Drops in a population of normal subjects by measuring corneal epithelial permeability...

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Medical and Biotech [MESH] Definitions

Ophthalmic solutions that include LUBRICANTS and WETTING AGENTS such as POLYETHYLENE GLYCOL; HYPROMELLOSE; GLYCEROL; PROPYLENE GLYCOL. They are used to treat conditions caused by deficient tear production such as DRY EYE SYNDROME.

The administration of therapeutic agents drop by drop, as eye drops, ear drops, or nose drops. It is also administered into a body space or cavity through a catheter. It differs from irrigation in that the irrigate is removed within minutes, but the instillate is left in place.

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The dioptric adjustment of the EYE (to attain maximal sharpness of retinal imagery for an object of regard) referring to the ability, to the mechanism, or to the process. Ocular accommodation is the effecting of refractive changes by changes in the shape of the CRYSTALLINE LENS. Loosely, it refers to ocular adjustments for VISION, OCULAR at various distances. (Cline et al., Dictionary of Visual Science, 4th ed)

Oleagenous substances used topically to soothe, soften or protect skin or mucous membranes. They are used also as vehicles for other dermatologic agents.

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