Utility of Versican and Hyaluronan Measurement in Induced Sputum as Biomarkers of Asthma

2014-08-27 03:19:12 | BioPortfolio


The purpose of this study is to determine the role of versican and hyaluronan measurements in induced sputum as biomarkers of asthma. Enroll 10 subjects with mild persistent asthma who are not receiving treatment with a controller therapy.


We will compare spirometry, eNO and sputum measurements of versican and hyaluronan before and after treatment with fluticasone 220 ug/bid.

Study Design

Allocation: Non-Randomized, Control: Active Control, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Allergic Asthma


Inhaled corticosteroid (fluticasone)


Associated Scientists to Help Minimize Allergies
United States


Active, not recruiting


Associated Scientists to Help Minimize Allergies

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:19:12-0400

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Medical and Biotech [MESH] Definitions

A STEROID with GLUCOCORTICOID RECEPTOR activity that is used to manage the symptoms of ASTHMA; ALLERGIC RHINITIS, and ATOPIC DERMATITIS.

A drug combination of fluticasone and salmeterol that is used as an inhaler formulation to manage the symptoms of ASTHMA and CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

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