Adaptive Cardiac Resynchronization Therapy Study

2014-08-27 03:19:13 | BioPortfolio


The purpose of this study is to show that Adaptive CRT is at least as good at optimizing a patient's cardiac resynchronization therapy (CRT) as the current method of using an echocardiogram. Adaptive CRT (aCRT) is an implantable heart failure device feature that attempts to optimize CRT without echocardiographic testing.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Heart Failure


Cardiac Resynchronization Therapy-Defibrillator (CRT-D), Adaptive CRT (aCRT) Pacing


West Virginia
United States




Medtronic Cardiac Rhythm Disease Management

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:19:13-0400

Clinical Trials [3183 Associated Clinical Trials listed on BioPortfolio]

Adaptive CRT Effect on Electrical Dyssynchrony

The purpose of this study is to better understand how adaptive cardiac resynchronization therapy (aCRT) might benefit patients. aCRT works by sometimes giving stimulation to only the left...

B-Left HF: Biventricular Versus Left Univentricular Pacing With Implantable Cardiac Defibrillator (ICD) Back-Up in Heart Failure Patients

The purpose of this study is to demonstrate that biventricular pacing (BiV) and left univentricular (left ventricular [LV] only) pacing are safe and effective for cardiac resynchronization...

Application of Right Atrial Left Ventricular Fusion Pacing in Patients With CRT Indications

This study is designed to assess the clinical outcomes of Left-Ventricular (LV) fusion pacing compared to Bi-Ventricular (BV) pacing, also known as Cardiac Resynchronization Therapy (CRT),...

Left Ventricular Septal Pacing: Potential Application for Cardiac Resynchronization Therapy

In cardiac resynchronization therapy (CRT), biventricular pacing is performed by pacing the right ventricle (RV) and epicardium of the left ventricular (LV) postero-lateral wall. A signifi...

Stem Cells and Resynchronization Cardiac

Same patients with dilated myocardiopathies with large areas of fibrosis has not been as successful after Cardiac Resynchronization Therapy, for Heart Failure patients in functional class ...

PubMed Articles [16466 Associated PubMed Articles listed on BioPortfolio]

Long-term Reverse Remodeling by Cardiac Resynchronization Therapy with MultiPoint Pacing: A Feasibility Study of Noninvasive Hemodynamics Guided Device Programming.

Cardiac resynchronization therapy (CRT) with multipoint left ventricular (LV) pacing (MultiPoint™ Pacing [MPP]) improves acute hemodynamics and chronic outcomes over conventional biventricular pacin...

Super-response to cardiac resynchronization therapy reduces appropriate implantable cardioverter-defibrillator therapy: comment.

Super-response to cardiac resynchronization therapy reduces appropriate implantable cardioverter-defibrillator therapy: comment-Authors' reply.

Linking cross-bridge cycling kinetics to response to cardiac resynchronization therapy: a multiscale modelling study.

Cardiac resynchronization therapy (CRT) is currently the most widely used treatment for heart failure patients with left bundle branch block (LBBB). In recent years, the presence of septal rebound str...

Atrioventricular optimization in cardiac resynchronization therapy with quadripolar leads: should we optimize every pacing configuration including multi-point pacing?

This study aims to define an atrioventricular (AV) delay optimization method for cardiac resynchronization therapy (CRT) with a quadripolar left ventricular (LV) lead based on intrinsic conduction int...

Medical and Biotech [MESH] Definitions

The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.

Types of artificial pacemakers with implantable leads to be placed at multiple intracardial sites. They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles. They may or may not include defibrillating electrodes (IMPLANTABLE DEFIBRILLATORS) as well.

Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.

Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).

More From BioPortfolio on "Adaptive Cardiac Resynchronization Therapy Study"

Quick Search


Searches Linking to this Trial