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Efficacy of Extended Release Tramadol for Treating Prescription Opioid Withdrawal

2014-08-27 03:19:13 | BioPortfolio

Summary

Prescription opioid addiction is a growing public health problem and more pharmacologic treatments are needed because current approved medications have had limited patient acceptance (naltrexone), limited availability (methadone), and concerns about misuse and diversion (methadone and buprenorphine). Tramadol is a currently approved medication used to treat moderate-severe pain, and initial studies demonstrate that it may be useful for treatment of the uncomfortable syndrome of opioid withdrawal without producing euphoric effects. This study will determine whether two different doses of extended release tramadol can treat opioid withdrawal and whether tramadol itself produces withdrawal after it is no longer taken.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Substance Withdrawal Syndrome

Intervention

Tramadol, Placebo

Location

University of Kentucky
Lexington
Kentucky
United States
40502

Status

Recruiting

Source

University of Kentucky

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:13-0400

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Medical and Biotech [MESH] Definitions

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Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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