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Calcium Dobesilate for Chronic Venous Wounds

2014-08-27 03:19:13 | BioPortfolio

Summary

The objective of the study is to assess the efficacy of calcium dobesilate for treating chronic venous wounds.

The hypothesis is that venous ulcers treated with standards measures (compressive measures) and calcium dobesilate will heal-up better than venous ulcers treated with standards measures (compressive measures) and placebo.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Ulcer

Intervention

Calcium Dobesilate

Location

Hospital de Cabueñes
Gijon
Asturias
Spain
33394

Status

Recruiting

Source

Fundacion Iberoamericana Itaca

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:13-0400

Clinical Trials [584 Associated Clinical Trials listed on BioPortfolio]

the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD

To investigate the feasibility of calcium dobesilate in the treatment of microvascular injury provides new ideas and theoretical basis for the prevention and treatment of chronic renal fai...

Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease

Haemorrhoids are vascular cushions in the anal canal that help in the control of stool. When inflamed they become pathological and may present with protrusion and bleeding. A randomized, t...

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The purpose of this study is to evaluate the safety and efficacy of vonoprazan tablets (Takecab tablets) in patients with gastric ulcer, duodenal ulcer, and reflux esophagitis in the routi...

Calcium Metabolism in Asian Adolescents

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PubMed Articles [1934 Associated PubMed Articles listed on BioPortfolio]

Calcium dobesilate: A drug treatment for diabetic retinopathy can negatively interfere with the measurement of glycated albumin using the enzymatic method.

We reported that calcium dobesilate, a vasoprotective agent mainly used for diabetic retinopathy (DR), negatively interferes with glycated albumin (GA) assays involving enzymatic methods.

The Effect of Calcium Dobesilate on Liver Damage in Experimental Obstructive Jaundice.

Purpose/Aim of the study: Inflammation and oxidative stress are two significant factors affecting the degree of liver damage in obstructive jaundice. The aim of this study was to evaluate the effect o...

Mechanisms of retinal neuroprotection of calcium dobesilate: therapeutic implications.

Novel Image-Based Analysis for Reduction of Clinician-Dependent Variability in Measurement of the Corneal Ulcer Size.

To assess variability in corneal ulcer measurements between ophthalmologists and reduce clinician-dependent variability using semiautomated segmentation of the ulcer from photographs.

Porcine stomachs with and without gastric ulcer differ in Lactobacillus load and strain characteristics.

Although Lactobacillus species are recognized as normal inhabitants of porcine gastric mucosa, the association of these bacteria with health status or gastric ulcer disease has never been considered. ...

Medical and Biotech [MESH] Definitions

A drug used to reduce hemorrhage in diabetic retinopathy.

A PEPTIC ULCER located in the DUODENUM.

Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.

Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.

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