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A Study to See the Effect of ICA-105665 in Photosensitive Epilepsy Patients

2014-07-23 21:12:45 | BioPortfolio

Summary

The purpose of this study is to determine the effects of ICA-105665 on the photoparoxysmal electroencephalography (EEG) response in photosensitive epilepsy patients exposed to intermittent photic stimulation.

Description

Subjects with epilepsy with a documented photoparoxysmal response to intermittent photic stimulation will participate. Four subjects will be enrolled at each dose level and will receive a single dose of placebo and a single dose of ICA-105665 during the study, each followed by intermittent photic stimulation. The effects of ICA-105665 on the photoparoxysmal EEG response of each group will be reviewed before the dose is selected for each subsequent group of subjects.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Photosensitive Epilepsy

Intervention

ICA-105665

Location

Little Rock
Arkansas
United States
72205

Status

Recruiting

Source

Icagen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:12:45-0400

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Epilepsy is defined as a disorder of brain function characterized by recurrent seizures that have a sudden onset.  (Oxford Medical Dictionary).  A seizure is caused by a sudden burst of excess electrical activity in the brain, causing a tempora...


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