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Clinical Efficacy and Safety of Autologous Cultured Keratinocyte Cell on Severe Burn Wood

2014-07-23 21:12:45 | BioPortfolio

Summary

The efficacy and safety of Autologous cultured keratinocyte cell on severe burn wound.

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Burn Wound

Intervention

Autologous cultured keratinocyte cell

Location

Hangang Sacred Heart Hospital
Seoul
Korea, Republic of
150-030

Status

Enrolling by invitation

Source

Modern Cell and Tissue Technology

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:12:45-0400

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Medical and Biotech [MESH] Definitions

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

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A secreted matrix metalloproteinase that may play a role in matrix degradation during WOUND HEALING. It is expressed at high levels by KERATINOCYTES, suggesting its role in keratinocyte migration.

A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

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