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Necrotizing Entercolitis (Nec) and B. Lactis in Premature Babies

2014-08-27 03:19:18 | BioPortfolio

Summary

The purpose of the trial is to demonstrate the effect of B. lactis in reducing the incidence of Necrotizing Entercolitis (NEC) compared to placebo in preterm infants.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Infant Nutrition

Intervention

Probiotic supplementation, Milk containing placebo

Location

University of Witwatersrand & Chris Hani Baragwanath Hospital
Bertsham
South Africa
2013

Status

Recruiting

Source

Nestlé Nutrition Corporate

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:18-0400

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Digestion of Human Milk Oligosaccharides by Bifidobacterium breve in the Premature Infant.

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Medical and Biotech [MESH] Definitions

Liquid formulations for the nutrition of INFANTS, useful for those with special needs or MILK HYPERSENSITIVITY or those whose mothers are unable to breastfeed (BREAST FEEDING).

Allergic reaction to milk (usually cow's milk) or milk products. MILK HYPERSENSITIVITY should be differentiated from LACTOSE INTOLERANCE, an intolerance to milk as a result of congenital deficiency of lactase.

Nutrition of a mother which affects the health of the FETUS and INFANT as well as herself.

Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)

Disorders caused by nutritional imbalance, either overnutrition or undernutrition, occurring in infants ages 1 month to 24 months.

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