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The Effect of Protandim on Non-alcoholic Steatohepatitis

2014-07-23 21:13:20 | BioPortfolio

Summary

The purpose of this study is to evaluate the effect of Protandim on the degree of liver injury after one year of supplementation. Protandim is a nutritional supplement composed of the following 5 botanical extracts: Bacopa Moniera extract, Milk Thistle extract, Ashwagandha powder, Green tea, and Turmeric extract. Protandim is commercially available and can be purchased without a prescription. Our findings could lead to a better understanding of the role of oxidative stress and antioxidant therapy in NASH and may ultimately help improve patient care.

Hypothesis #1: Protandim will lead to a significant improvement in NAS compared to placebo.

Hypothesis #2: Protandim will lead to a significant decrease in serum markers of oxidative stress and liver chemistry tests.

Hypothesis #3: Protandim will lead to decreased levels of TNF- α compared to placebo.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Non-Alcoholic Steatohepatitis

Intervention

Protandim, Placebo

Location

University of Colorado at Denver and Health Sciences Center
Denver
Colorado
United States
80045

Status

Enrolling by invitation

Source

University of Colorado, Denver

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:13:20-0400

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