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A Trial Investigating the Pharmacokinetic (Mode of Action in the Body) and Safety Profiles of NN1250 in Subjects With Various Degrees of Impaired Liver Function and in Subjects With Normal Liver Function

2014-08-27 03:19:23 | BioPortfolio

Summary

This trial is conducted in Europe. The aim of this clinical trial is to evaluate if the pharmacokinetic and safety profiles of NN1250 are altered to such an extent that the dose should be adjusted in subjects with impaired liver function compared to the dose for subjects with normal liver function.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Diabetes Mellitus

Intervention

NN1250

Location

Bratislava
Slovakia
833 05

Status

Completed

Source

Novo Nordisk

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:23-0400

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Medical and Biotech [MESH] Definitions

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Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

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