BioCleanse Tibialis Tendon Anterior Cruciate Ligament (ACL) Study

2014-07-23 21:13:21 | BioPortfolio


To compare the outcomes of ACL reconstruction using tendons from two tibialis allograft donor age groups.


This study will compare tibialis tendons recovered from two different groups of donors. One group of tendons will be recovered from donors 18-45 years of age and the second group of tendons will be recovered from donors 65-75 years of age. A total of 40 subjects will be enrolled and randomized into one of the two groups and have ACL reconstruction performed with the tendon in the group they were randomized into. Follow up is for two years.

Study Design

Allocation: Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Anterior Cruciate Ligament Rupture


BioCleanse Tibialis tendon, Tibialis Tendon Allograft from donor 65-75 years of age


The Orthopedic Clinic, Assoc
United States




RTI Biologics

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:13:21-0400

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PubMed Articles [2081 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

Surgical procedure by which a tendon is incised at its insertion and placed at an anatomical site distant from the original insertion. The tendon remains attached at the point of origin and takes over the function of a muscle inactivated by trauma or disease.

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Tendon that connects the muscles in the back of the calf to the HEEL BONE.

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