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Changes in the Renal Excretion of Neramexane by Acidification of Urinary pH Study With and Without Application of a Urinary pH Acidification Regimen

2014-08-27 03:19:31 | BioPortfolio

Summary

Primary:

- To assess the influence of acidified urinary pH on the renal excretion of Neramexane

Secondary:

- To assess the influence of acidified urinary pH on the renal excretion of N-OH Neramexane

- To assess the steady state plasma pharmacokinetics (PK) of Neramexane and N-OH Neramexane under physiological conditions and under the conditions of urine acidification

- To assess safety and tolerability of a repeated dose treatment of Neramexane under physiological conditions and under the conditions of urine acidification

Study Design

Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Healthy

Intervention

Neramexane

Status

Not yet recruiting

Source

Merz Pharmaceuticals GmbH

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:31-0400

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