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Effectiveness of Telescopic Magnification in the Treatment of Amblyopia

2014-08-27 03:19:36 | BioPortfolio

Summary

Amblyopia is a visual impairment of one eye that results from disuse of that eye during early brain development. The standard treatment for amblyopia consists of patching or pharmacological penalization of the sound eye. Unfortunately, approximately 50% of amblyopic children do not respond to these therapies, with poor compliance being a major factor in treatment failure. One new treatment strategy involves patching the sound eye while using a telescopic device on the amblyopic eye to magnify the images formed in the amblyopic eye. Children were randomized to receive either daily patching of the sound eye for 30 minutes only (patching only group), or daily patching of the sound eye for 30 minutes plus simultaneous use of a telescopic device by the amblyopic eye during patching (patching plus telescope group).

Description

The goal of the present investigation was to conduct a prospective randomized clinical study to further evaluate the effectiveness of telescopic magnification plus patching vs patching alone on different types of amblyopia in patients who had failed previous treatment.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Amblyopia

Intervention

Patching, Telescopic magnification

Location

The Hospital for Sick Children
Toronto
Ontario
Canada

Status

Completed

Source

The Hospital for Sick Children

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:36-0400

Clinical Trials [71 Associated Clinical Trials listed on BioPortfolio]

Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds

The purpose of this study is: - To compare the effectiveness of weekend atropine plus near activities and daily patching plus near activities for moderate amblyopia (20/40 to 20/1...

Trial Comparing Part-Time Versus Full-Time Patching for Severe Amblyopia

The goals of this study are: - To determine whether the visual acuity improvement obtained with part-time (6 hours) patching is equivalent to the visual acuity improvement obtaine...

Anisometropia Amblyopia Improved by Perceptual Learning and Patching

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Docosahexaenoic Acid (DHA) Supplementation in Amblyopia

This study evaluates the addition of docosahexaenoic acid (DHA) to eye patching in the treatment of residual amblyopia in children ages 3 to 18 years old. Two thirds of participants will r...

Increasing Patching for Amblyopia in Children 3 to < 8 Years Old

This study is designed to evaluate the effectiveness of increasing prescribed patching treatment from 2 to 6 daily hours after visual acuity has stabilized with initial treatment and ambly...

PubMed Articles [110 Associated PubMed Articles listed on BioPortfolio]

Cerebral structural characteristics in children with unilateral amblyopia: a MRI study.

To study the mechanism of the development of amblyopia using the analysis of brain grey matter parameters. The areas primarily associated with visual cortex in children with amblyopia were analyzed.

Audiovisual perception in amblyopia: A review and synthesis.

Amblyopia is a common developmental sensory disorder that has been extensively and systematically investigated as a unisensory visual impairment. However, its effects are increasingly recognized to ex...

Therapeutic contact lenses vs. tight bandage patching and pain following pterygium excision: a prospective randomized controlled study.

The immediate postoperative management of patients undergoing pterygium excision usually includes eye patching in order to alleviate pain and prevent accidental tissue damage. Commonly applied tight p...

Evaluation of the Effects of the Occlu-Pad for the Management of Anisometropic Amblyopia in Children.

In recent years, amblyopia treatment device that can be used with both eyes open have been reported. The Occlu-pad is a device that can present images of tablet terminals to one eye only under binocul...

Does magnification of SEM image influence quantification of particulate matters deposited on vegetation foliage.

The metrics used to quantify the particles on the leaf surface can serve as indicators for the quality of the atmospheric environment and is employed to evaluate the ecosystem services that plants can...

Medical and Biotech [MESH] Definitions

A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.

Pieces of glass or other transparent materials used for magnification or increased visual acuity.

An extract of absinthium and other bitter herbs, containing 60% alcohol. Prolonged ingestion causes nervousness, convulsions, trismus, amblyopia, optic neuritis, and mental deterioration. (Dorland, 27th ed)

Cognitive and emotional processes encompassing magnification of pain-related stimuli, feelings of helplessness, and a generally pessimistic orientation.

Use of optic and geometric techniques to enhance radiographic image quality and interpretation. It includes use of microfocal X-ray tubes and intensifying fluoroscopic screens.

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