Effectiveness of Telescopic Magnification in the Treatment of Amblyopia

2014-08-27 03:19:36 | BioPortfolio


Amblyopia is a visual impairment of one eye that results from disuse of that eye during early brain development. The standard treatment for amblyopia consists of patching or pharmacological penalization of the sound eye. Unfortunately, approximately 50% of amblyopic children do not respond to these therapies, with poor compliance being a major factor in treatment failure. One new treatment strategy involves patching the sound eye while using a telescopic device on the amblyopic eye to magnify the images formed in the amblyopic eye. Children were randomized to receive either daily patching of the sound eye for 30 minutes only (patching only group), or daily patching of the sound eye for 30 minutes plus simultaneous use of a telescopic device by the amblyopic eye during patching (patching plus telescope group).


The goal of the present investigation was to conduct a prospective randomized clinical study to further evaluate the effectiveness of telescopic magnification plus patching vs patching alone on different types of amblyopia in patients who had failed previous treatment.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment




Patching, Telescopic magnification


The Hospital for Sick Children




The Hospital for Sick Children

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:19:36-0400

Clinical Trials [78 Associated Clinical Trials listed on BioPortfolio]

Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds

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The goals of this study are: - To determine whether the visual acuity improvement obtained with part-time (6 hours) patching is equivalent to the visual acuity improvement obtaine...

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To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Docosahexaenoic Acid (DHA) Supplementation in Amblyopia

This study evaluates the addition of docosahexaenoic acid (DHA) to eye patching in the treatment of residual amblyopia in children ages 3 to 18 years old. Two thirds of participants will r...

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PubMed Articles [115 Associated PubMed Articles listed on BioPortfolio]

Cerebral structural characteristics in children with unilateral amblyopia: a MRI study.

To study the mechanism of the development of amblyopia using the analysis of brain grey matter parameters. The areas primarily associated with visual cortex in children with amblyopia were analyzed.

Audiovisual perception in amblyopia: A review and synthesis.

Amblyopia is a common developmental sensory disorder that has been extensively and systematically investigated as a unisensory visual impairment. However, its effects are increasingly recognized to ex...

Therapeutic contact lenses vs. tight bandage patching and pain following pterygium excision: a prospective randomized controlled study.

The immediate postoperative management of patients undergoing pterygium excision usually includes eye patching in order to alleviate pain and prevent accidental tissue damage. Commonly applied tight p...

Does magnification of SEM image influence quantification of particulate matters deposited on vegetation foliage.

The metrics used to quantify the particles on the leaf surface can serve as indicators for the quality of the atmospheric environment and is employed to evaluate the ecosystem services that plants can...

Global and regional estimates of prevalence of amblyopia: A systematic review and meta-analysis.

Amblyopia is one of the most important causes of vision impairment in the world, especially in children. Although its prevalence varies in different parts of the world, no study has evaluated its prev...

Medical and Biotech [MESH] Definitions

A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.

Pieces of glass or other transparent materials used for magnification or increased visual acuity.

An extract of absinthium and other bitter herbs, containing 60% alcohol. Prolonged ingestion causes nervousness, convulsions, trismus, amblyopia, optic neuritis, and mental deterioration. (Dorland, 27th ed)

Cognitive and emotional processes encompassing magnification of pain-related stimuli, feelings of helplessness, and a generally pessimistic orientation.

Use of optic and geometric techniques to enhance radiographic image quality and interpretation. It includes use of microfocal X-ray tubes and intensifying fluoroscopic screens.

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