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Prolonged Fasting and FGF-21 Levels

2014-08-27 03:19:38 | BioPortfolio

Summary

This study will look at the effect of 72 hours of fasting (not eating) on levels of proteins that are involved in metabolism. These proteins will be measured in blood and fat tissue. The investigators' hypothesis is that fasting will cause changes in these proteins.

Description

The purpose of this study is to examine how fasting affects levels of several proteins involved in metabolism. Studies done in animals show that fasting causes changes in proteins involved in fatty acid metabolism and the structure of fat cells. In this study, we wish to learn whether these factors change when humans are fasted.

This study will involve a 72 hour fast. During the fast, study participants may consume only water and vitamins. Participants will spend 3 days and nights in the Clinical Research Center at the Beth Israel Deaconess Medical Center. Daily blood samples will be taken, as well as two fat samples, one before the fast and one at the end of the fast.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Conditions

Metabolism

Intervention

Fasting

Location

Beth Israel Deaconess Medical Center
Boston
Massachusetts
United States
02215

Status

Recruiting

Source

Beth Israel Deaconess Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:38-0400

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