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This study will look at the effect of 72 hours of fasting (not eating) on levels of proteins that are involved in metabolism. These proteins will be measured in blood and fat tissue. The investigators' hypothesis is that fasting will cause changes in these proteins.
The purpose of this study is to examine how fasting affects levels of several proteins involved in metabolism. Studies done in animals show that fasting causes changes in proteins involved in fatty acid metabolism and the structure of fat cells. In this study, we wish to learn whether these factors change when humans are fasted.
This study will involve a 72 hour fast. During the fast, study participants may consume only water and vitamins. Participants will spend 3 days and nights in the Clinical Research Center at the Beth Israel Deaconess Medical Center. Daily blood samples will be taken, as well as two fat samples, one before the fast and one at the end of the fast.
Intervention Model: Single Group Assignment, Masking: Open Label
Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center
Published on BioPortfolio: 2014-08-27T03:19:38-0400
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Abstaining from all food.
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