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Everolimus Dose Finding Study for Stage IV or Recurrent Cervical Cancer

2014-08-27 03:19:43 | BioPortfolio

Summary

This Phase 1, single-site, dose-escalation study is being conducted to determine the maximum tolerated dose (MTD) of RAD001 as part of a specified combination regimen.

Description

This Phase 1, single-site, dose-escalation study is being conducted to determine the MTD of RAD001 as part of a specified combination regimen. The combination regimen will be standard field whole pelvic RT in combination with cisplatin at 40mg/m2 weekly with RAD001 at dose escalation daily starting at 5 mg qod, then 5 mg qd, then 10 mg qd during the period of whole pelvic radiation therapy.

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Cervical Cancer

Intervention

RAD001, Cisplatin, External Beam Whole Pelvis Radiation Therapy

Status

Withdrawn

Source

Accelerated Community Oncology Research Network

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:43-0400

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