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Establishment of Optimal Transfusion Threshold During Spine Surgery

2014-08-27 03:19:44 | BioPortfolio

Summary

The purpose of this study is to determine whether a higher threshold for transfusion with red blood cells improves the tissue oxygenation.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care

Conditions

Anemia

Intervention

Allowed drop in hemoglobin to level between 4,5-5,6 mmol/L, Allowed drop in hemoglobin to level between 5,6-6,5 mmol/L

Location

Rigshospitalet
Copenhagen
Østerbro
Denmark
2100

Status

Recruiting

Source

Rigshospitalet, Denmark

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:44-0400

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Medical and Biotech [MESH] Definitions

The administration of therapeutic agents drop by drop, as eye drops, ear drops, or nose drops. It is also administered into a body space or cavity through a catheter. It differs from irrigation in that the irrigate is removed within minutes, but the instillate is left in place.

Products of non-enzymatic reactions between GLUCOSE and HEMOGLOBIN A, occurring as a minor fraction of the hemoglobin components of human erythrocytes. Hemoglobin A1c is hemoglobin A with glucose covalently bound to the terminal VALINE of the beta chain. Glycated hemoglobin A is used as an index of the average blood sugar level over a lifetime of erythrocytes.

BREATH HOLDING; VASOCONSTRICTION; and a drop in HEART RATE in response to submersion of the face in cold water.

Termination of pregnancy under conditions allowed under local laws. (POPLINE Thesaurus, 1991)

A condition of abnormally high level of PHOSPHATES in the blood, usually significantly above the normal range of 0.84-1.58 mmol per liter of serum.

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