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Huperzine for Cognitive and Functional Impairment in Schizophrenia

2014-07-24 14:11:46 | BioPortfolio

Summary

Huperzine is a natural plant product with procognitive properties in patients with Alzheimer's disease. Cognitive difficulties hamper functioning in schizophrenia as well. The present study will investigate whether huperzine improves cognition and functioning in patients with schizophrenia.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Schizophrenia

Intervention

placebo, huperzine 0.2 mg BID, huperzine 0.4 mg BID

Location

Yale University School of Medicine
New Haven
Connecticut
United States
06519

Status

Recruiting

Source

Biomedisyn Corporation

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:11:46-0400

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PubMed Articles [1729 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

A plant genus of the family LYCOPODIACEAE. Members contain huperzine, one of the CHOLINESTERASE INHIBITORS.

A chronic form of schizophrenia characterized primarily by the presence of persecutory or grandiose delusions, often associated with hallucination.

A type of schizophrenia characterized by abnormality of motor behavior which may involve particular forms of stupor, rigidity, excitement or inappropriate posture.

An obsolete concept, historically used for childhood mental disorders thought to be a form of schizophrenia.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

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Psychiatry
Psychiatry is the study of mental disorders and their diagnosis, management and prevention.  Conditions include schizophrenia, severe depression and panic disorders among others. There are pharmaceutical treatments as well as other therapies to help...


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