Acute Achilles Repair With or Without OrthADAPT Augmentation

2014-07-23 21:13:35 | BioPortfolio


The purpose of this study is to assess the clinical performance of the OrthADAPT Bioimplant in patients with acute mid-substance Achilles tendon tears requiring surgical repair.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment


Achilles Tendon Tear


Achilles repair with OrthADAPT augmentation, Achilles repair without OrthADAPT Augmentation


Orthopaedic Institute of Central Jersey
Sea Girt
New Jersey
United States




Synovis Surgical Innovations

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:13:35-0400

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Operative Versus Non-Operative Treatment of Achilles Tendon Rupture

This study is intended to determine whether the optimal treatment of acute Achilles tendon ruptures is surgical repair or functional bracing. Our hypotheses are surgical repair will: 1) R...

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Peroneal and Achilles tendon tears are common diseases that present challenges to surgeons due to tendon adhesion complications. Functional recovery is compromised by limiting post-operati...

Analytical and Functional Evaluation of Recovery Following Acute Rupture of the Achilles Tendon and Surgical Repair in Young Patients

Acute rupture of the Achilles tendon is a very frequent sports injury. Surgical repair is the usual treatment in young subjects, and although the optimal technique is still a matter of deb...

PubMed Articles [2884 Associated PubMed Articles listed on BioPortfolio]

Is open acute Achilles tendon rupture repair still justified? A single center experience and critical appraisal of the literature.

Acute Achilles tendon ruptures are injuries with multiple treatment strategies with possibly far reaching consequences. Open repair is associated with a high complication rate, whereas percutaneous te...

The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial.

Treatment strategies for Achilles tendon rupture vary considerably, and clinical outcome may depend on the magnitude of tendon elongation after surgical repair. The aim of this project was to examine ...

Achilles tendinosis does not always precede Achilles tendon rupture.

Degenerative change is a typical histologic finding of Achilles tendinosis and is thought to be a factor associated with Achilles tendon rupture; however, this relationship remains controversial. Ther...

Association of Achilles tendon thickness and LDL-cholesterol levels in patients with hypercholesterolemia.

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A comparison of three methods of skin closure following repair of Achilles tendon rupture.

Meticulous skin closure is required to avoid wound problems after Achilles tendon surgery. The purpose of our study was to compare postoperative complication rate, operation time, clinical outcome and...

Medical and Biotech [MESH] Definitions

The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.

A DNA repair enzyme that catalyzes DNA synthesis during base excision DNA repair. EC

The repair of DOUBLE-STRAND DNA BREAKS by rejoining the broken ends of DNA to each other directly.

Repair of DNA DAMAGE by exchange of DNA between matching sequences, usually between the allelic DNA (ALLELES) of sister chromatids.

Tendon that connects the muscles in the back of the calf to the HEEL BONE.

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