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Observational Prospective Study on Patients Treated With Norditropin®

2014-08-27 03:19:58 | BioPortfolio

Summary

This study is conducted in Europe. The aim of this observational study is to investigate the effectiveness and safety of real-life treatment with Norditropin®. The study population will consist of children and adults who are already being treated with Norditropin® or who are candidates for treatment with Norditropin®.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Growth Hormone Deficiency (GHD)

Intervention

somatropin, somatropin

Location

Prov. de Buenos Aires
Argentina
B1636DSU

Status

Enrolling by invitation

Source

Novo Nordisk

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:19:58-0400

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Medical and Biotech [MESH] Definitions

A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.

A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.

An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.

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A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.

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