Study Evaluating Neratinib in Combination With Vinorelbine in Subjects With Advanced or Metastatic Solid Tumors

2014-08-27 03:20:03 | BioPortfolio


The purposes of this study are to evaluate the safety and tolerability of neratinib in combination with vinorelbine at the maximum tolerated dose (MTD) determined in a previous study, or to determine a lower MTD of the two drugs, as well as to obtain preliminary information on whether the combination of the two drugs has any effect on solid tumors in Japanese patients.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Advanced Malignant Solid Tumors


treatment with neratinib (HKI-272) + vinorelbine




Active, not recruiting



Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:20:03-0400

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