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Study Evaluating Neratinib in Combination With Vinorelbine in Subjects With Advanced or Metastatic Solid Tumors

2014-08-27 03:20:03 | BioPortfolio

Summary

The purposes of this study are to evaluate the safety and tolerability of neratinib in combination with vinorelbine at the maximum tolerated dose (MTD) determined in a previous study, or to determine a lower MTD of the two drugs, as well as to obtain preliminary information on whether the combination of the two drugs has any effect on solid tumors in Japanese patients.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Advanced Malignant Solid Tumors

Intervention

treatment with neratinib (HKI-272) + vinorelbine

Location

Shunto-gun
Shizuoka
Japan
411-8777

Status

Active, not recruiting

Source

Wyeth

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:20:03-0400

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