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Raltegravir Switch for Toxicity or Adverse Events

2014-08-27 03:20:03 | BioPortfolio

Summary

This study aims to verify the persistent control of the virus replication at 48 weeks after the simplification to tenofovir + emtricitabine + raltegravir or to lamivudine+abacavir+raltegravir in patients with optimal virological suppression without any virological failure to previous combined antiretroviral therapies needing a therapeutic switch for toxicity related issues or adverse events.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

HIV/AIDS

Intervention

tenofovir emtricitabine raltegravir, Lamivudine Abacavir Raltegravir, Abacavir free

Location

Policlinico A. Gemelli
Rome
Italy
00168

Status

Recruiting

Source

Catholic University of the Sacred Heart

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:20:03-0400

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Medical and Biotech [MESH] Definitions

A pharmaceutical preparation of emtricitabine and tenofovir that is used as an ANTI-HIV AGENT in the treatment and prevention of HIV INFECTIONS.

A pharmaceutical preparation that contains emtricitabine, rilpivirine and tenofovir disoproxil fumarate. It is used to treat HIV INFECTIONS.

A pharmaceutical preparation of the ANTI-HIV AGENTS elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate that is used in the treatment of HIV INFECTIONS.

A pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.

Inhibitor or Reverse Transcriptases or of RNA-dIrected DNA polymerase.

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