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Effects of Ketamine on Human Bladders and Its Possible Mechanisms

2014-07-23 21:13:40 | BioPortfolio

Summary

This study is aimed to evaluate the relationship between ketamine abused and bladder dysfunction and its possible mechanisms.

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Conditions

Cystitis

Intervention

ketamine

Location

Taipei Medical University-Wan Fang Hospital
Taipei
Taiwan

Status

Enrolling by invitation

Source

Taipei Medical University WanFang Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:13:40-0400

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PubMed Articles [218 Associated PubMed Articles listed on BioPortfolio]

Complete reversal of the clinical symptoms and image morphology of ketamine cystitis after intravesical hyaluronic acid instillation: A case report.

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Medical and Biotech [MESH] Definitions

A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.

A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.

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Frequent URINATION at night that interrupts sleep. It is often associated with outflow obstruction, DIABETES MELLITUS, or bladder inflammation (CYSTITIS).

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