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This study is an observational surveillance study to identify adults 50 years and older who present to a study healthcare facility with signs and symptoms of Community-Acquired Pneumonia and/or Invasive Pneumococcal Disease.
This active, prospective, population-based, surveillance study for CAP and IPD in adults 50 years and older will be conducted in Latin America, Asia, and Europe. One country from each of these regions will be selected and in each country, one surveillance area will be identified. Each surveillance area will be selected using the following criteria: 1) a well defined population of adults aged 50 years and older living in the surveillance area, 2) definable and limited number of study hospitals and outpatient clinics, 3) presence of high-quality in-hospital clinical microbiology testing including automated blood culture testing, 4) low rates (i.e., <5% per annum) of migration among adults aged 50 years and older, 5) ability to diagnose and treat adults with severe disease associated with CAP and/or IPD, 6) feasibility of obtaining information on healthcare utilization and healthcare system description (structure, referral, coordination/management, etc) and 7) the ability of the investigator to implement and sustain population-based surveillance for CAP and IPD over a two-year study period.
Time Perspective: Prospective
Community Acquired Pneumonia
Blood draw, ChestX-ray, urine specimen, Nasopharyngeal swab
Korea, Republic of
Published on BioPortfolio: 2014-08-27T03:21:06-0400
This is a generic sample collection study for collecting blood, stool, rectal swabs, nasal washes, nasopharyngeal aspirates, nasopharyngeal swabs, throat swabs, nasal swabs, and urine from...
The primary purpose of this study is to assess the contribution of a non-invasive sampling (pharyngeal swab) in the diagnosis of community based meningitis or meningo-encephalitis.
RATIONALE: Collecting and storing samples of blood, saliva, throat tissue, and urine from patients at high risk of nasopharyngeal cancer to test in the laboratory may help the study of can...
In an effort to identify genetic factors linked to the development of nasopharyngeal cancer (NPC), the researchers identified and sampled 2,394 individuals from Taiwanese families in which...
This study is being done with the purpose of trying to understand if and why transplant recipients may develop tolerance to their transplanted organ. Tolerance means being able to lower or...
While studying respiratory infections in Peru, we identified Venezuelan equine encephalitis virus (VEEV) in a nasopharyngeal swab, indicating that this alphavirus can be present in human respiratory s...
In recent decades, urine drug testing in the workplace has become common in many countries in the world. There have been several studies concerning the use of the urine specimen validity test (SVT) fo...
This article reports the concentrations of gamma-hydroxybutyrate (GHB) in femoral blood and bladder urine in a case series of drug intoxication deaths (N = 37). GHB was determined in blood (B-GHB) and...
Pre-exposure prophylaxis (PrEP) reduces risk of HIV infection for many gay and bisexual men (GBM); however, bacterial sexually transmitted infections (STIs) associated with decreasing condom use among...
Deviation in blood collection procedures is a central source of preanalytical variation affecting overall analytical and diagnostic precision. The order of draw of venous sampling is suspected to affe...
Methods or procedures used to obtain samples of URINE.
The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.
The technique of spraying a tissue specimen with a thin coat of a heavy metal such as platinum. The specimen is sprayed from an oblique angle, which results in the uneven deposition of the coating. The varying thicknesses create a shadow effect and give a three-dimensional appearance to the specimen.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
Health care (or healthcare) is the diagnosis, treatment, and prevention of disease, illness, injury, and other physical and mental impairments in humans. Health care is delivered by practitioners in medicine, chiropractic, dentistry, nursing, pharmacy, a...
Pneumonia (bronchopneumonia, lobar pneumonia and double pneumonia) is inflammation (swelling) of the tissue in one or both of your lungs. It is usually caused by an pneumococcal infection caused by bacteria called Streptococcus pneumoniae. However,...
Prostate cancer (cancer de prostata) Prostate cancer (cancer de prostata) is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostat...