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Pharmacodynamic Study of Two Lanthanum Carbonate Formulations in Healthy Adults

2014-07-24 14:13:42 | BioPortfolio

Summary

This study is being conducted to assess any potential differences in the absorption and excretion between two lanthanum carbonate formulations. This study is also being done to assess the safety and tolerability of the two lanthanum carbonate formulations.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Crossover Assignment, Masking: Open Label

Conditions

End Stage Renal Disease

Intervention

Lanthanum carbonate Granule Formulation, Lanthanum carbonate Chewable Tablets (Fosrenol)

Location

West Coast Clinical Trials, LLC
Cypress
California
United States
90630

Status

Completed

Source

Shire Pharmaceutical Development

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:13:42-0400

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PubMed Articles [1675 Associated PubMed Articles listed on BioPortfolio]

Case report of lanthanum deposition in the esophagus.

A 69-year-old woman had received hemodialysis for chronic renal failure and was taking lanthanum carbonate since 63 years of age. She presented with appetite loss and nausea. We performed esophagogas...

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A Novel OSSO-Type Chromium (III) Complex as Versatile Catalyst for Copolymerization of Carbon Dioxide with Epoxides.

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Effects of in utero exposure to lanthanum on neurological behavior in rat offspring.

The increasing use of rare-earth elements in various fields has raised concern from public heath perspective regarding their accumulation in human body. Long-term exposure to lanthanum, one of the fre...

Gas-Phase Reactivity of Carbonate Ions with Sulfur Dioxide: an Experimental Study of Clusters Reactions.

The reactivity of carbonate cluster ions with sulfur dioxide has been investigated in the gas phase by mass spectrometric techniques. SO promotes the displacement of carbon dioxide from carbonate clu...

Medical and Biotech [MESH] Definitions

Lanthanum. The prototypical element in the rare earth family of metals. It has the atomic symbol La, atomic number 57, and atomic weight 138.91. Lanthanide ion is used in experimental biology as a calcium antagonist; lanthanum oxide improves the optical properties of glass.

A field of chemistry which pertains to chemical compounds or ions that do not contain the element carbon (with the exception of carbon dioxide and compounds containing a carbonate radical, e.g., calcium carbonate).

A method of treating an ALLERGY by administering ALLERGENS, in liquid formulation or tablets, to the ORAL MUCOSA under the tongue.

Protein-mineral complexes that comprise substrates needed for the normal calcium-carbonate-phosphate homeostasis. Nanobacteria was the prior name for the particles which were originally thought to be microorganisms.

Elements of the lanthanoid series including atomic number 57 (LANTHANUM) through atomic number 71 (LUTETIUM).

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