Pharmacodynamic Study of Two Lanthanum Carbonate Formulations in Healthy Adults

2014-07-24 14:13:42 | BioPortfolio


This study is being conducted to assess any potential differences in the absorption and excretion between two lanthanum carbonate formulations. This study is also being done to assess the safety and tolerability of the two lanthanum carbonate formulations.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Crossover Assignment, Masking: Open Label


End Stage Renal Disease


Lanthanum carbonate Granule Formulation, Lanthanum carbonate Chewable Tablets (Fosrenol)


West Coast Clinical Trials, LLC
United States




Shire Pharmaceutical Development

Results (where available)

View Results


Published on BioPortfolio: 2014-07-24T14:13:42-0400

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PubMed Articles [1675 Associated PubMed Articles listed on BioPortfolio]

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Effects of in utero exposure to lanthanum on neurological behavior in rat offspring.

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Medical and Biotech [MESH] Definitions

Lanthanum. The prototypical element in the rare earth family of metals. It has the atomic symbol La, atomic number 57, and atomic weight 138.91. Lanthanide ion is used in experimental biology as a calcium antagonist; lanthanum oxide improves the optical properties of glass.

A field of chemistry which pertains to chemical compounds or ions that do not contain the element carbon (with the exception of carbon dioxide and compounds containing a carbonate radical, e.g., calcium carbonate).

A method of treating an ALLERGY by administering ALLERGENS, in liquid formulation or tablets, to the ORAL MUCOSA under the tongue.

Protein-mineral complexes that comprise substrates needed for the normal calcium-carbonate-phosphate homeostasis. Nanobacteria was the prior name for the particles which were originally thought to be microorganisms.

Elements of the lanthanoid series including atomic number 57 (LANTHANUM) through atomic number 71 (LUTETIUM).

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