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Biomarker Trial of Everolimus in Patients With Advanced Renal Cell Carcinoma

2014-08-27 03:24:57 | BioPortfolio

Summary

The purpose of this study is to determine if certain features of tumor specimens sampled prior to therapy can predict for the likelihood of responding to everolimus.

Description

- Participants will undergo a CT or ultrasound guided biopsy of an accessible tumor lesion before beginning the study medication.

- Everolimus tablets will be taken orally once a day. Participants will undergo a physical exam and will be asked questions about their general health and specific questions about any problems they might be having. Photographs will be taken of the tumor to assess the response to treatment. This will be done by a CT or MRI scan. Blood tests will be performed every 4 weeks. In addition, blood for research purposes will be done on day 1 of every other cycle. A urine test will be done every 4 weeks.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Renal Cell Carcinoma

Intervention

Everolimus

Location

Beth Israel Deaconess Medical Center
Boston
Massachusetts
United States
27710

Status

Recruiting

Source

Dana-Farber Cancer Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:24:57-0400

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