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Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Breast Cancer

2014-07-24 14:15:03 | BioPortfolio

Summary

This is a multicenter, open-label, two-arm, 2-stage, Phase 2 study of NKTR-102 in patients with metastatic or locally advanced breast cancer whose disease has failed prior taxane-based treatment in the metastatic setting.

Patients will be randomized 1:1 into one of two treatment arms. NKTR 102 will be administered at a dose level of 145 mg/m2 in both arms. In Arm A, NKTR-102 will be given on a q14d schedule. In Arm B, NKTR-102 will be given on a q21d schedule. Approximately 70 patients may be evaluated in this study with approximately 35 patients enrolled in each treatment arm.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Tumor

Intervention

NKTR-102, NKTR-102

Location

USC Norris Comprehensive Cancer Center
Los Angeles
California
United States
90089-9177

Status

Active, not recruiting

Source

Nektar Therapeutics

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:15:03-0400

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