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Evaluation of Power Doppler US Technique for the Diagnosis of Spondylarthropathy

2014-08-27 03:26:08 | BioPortfolio

Summary

The purpose of this study is to evaluate the interest of enthesis sonography for the diagnosis of spondylarthritis, in patients with uncertain diagnosis consulting for clinical symptoms suggestive of spondylarthritis

Description

Spondylarthritis (SPA) are the second most frequent inflammatory rheumatic disorders and, because it starts early in life and has a chronic progressive course, the impact of this disease on health resources and patient's life quality can be important. Because the characteritic signs of SPA, like radiological evidence of sacro-iliitis, appear late in time, the lag time between the onset first signs of SPA for the patient and the confirmed diagnosis can be very long (up to 8 years). Previous studies proved that patients who are affected by SPA are showing abnormal vascularization of peripheral enthesis more frequently than patients affected by other rheumatic diseases. Ultrasonography in B mode combined with power Doppler (PDUS) is a non invasive and highly sensitive toll which can detect enthesitis and abnormal vsacularization even for the patients who are not showing yet the evidence of SPA's symptomatology. Using PDUS as a early diagnosis tool could lead to the improvement of diagnostic procedures and therapeutic management of SpA and reduce the cost of diagnosis for patient and health insurances.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Spondylarthropathy

Location

Ambroise Paré Hospital
Boulogne Billancourt
France
92100

Status

Active, not recruiting

Source

Groupe Français d'Etude Génétique des Spondylarthropathies

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:26:08-0400

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PubMed Articles [0 Results]

None

Medical and Biotech [MESH] Definitions

A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.

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