Evaluation of Power Doppler US Technique for the Diagnosis of Spondylarthropathy

2014-08-27 03:26:08 | BioPortfolio


The purpose of this study is to evaluate the interest of enthesis sonography for the diagnosis of spondylarthritis, in patients with uncertain diagnosis consulting for clinical symptoms suggestive of spondylarthritis


Spondylarthritis (SPA) are the second most frequent inflammatory rheumatic disorders and, because it starts early in life and has a chronic progressive course, the impact of this disease on health resources and patient's life quality can be important. Because the characteritic signs of SPA, like radiological evidence of sacro-iliitis, appear late in time, the lag time between the onset first signs of SPA for the patient and the confirmed diagnosis can be very long (up to 8 years). Previous studies proved that patients who are affected by SPA are showing abnormal vascularization of peripheral enthesis more frequently than patients affected by other rheumatic diseases. Ultrasonography in B mode combined with power Doppler (PDUS) is a non invasive and highly sensitive toll which can detect enthesitis and abnormal vsacularization even for the patients who are not showing yet the evidence of SPA's symptomatology. Using PDUS as a early diagnosis tool could lead to the improvement of diagnostic procedures and therapeutic management of SpA and reduce the cost of diagnosis for patient and health insurances.

Study Design

Observational Model: Cohort, Time Perspective: Prospective




Ambroise Paré Hospital
Boulogne Billancourt


Active, not recruiting


Groupe Français d'Etude Génétique des Spondylarthropathies

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:26:08-0400

Clinical Trials [8 Associated Clinical Trials listed on BioPortfolio]

Study Evaluating Etanercept for the Treatment of Refractory Heel Enthesitis in Spondylarthropathy

To assess the efficacy and safety of Etanercept in patients with spondylarthropathy and refractory heel enthesitis.

Faecal Analyses in Spondyloarthritis Therapy

This study evaluates the intestinal microbiome and disease activity in patients with spondyloarthropathies receiving immunosuppressive therapy. Patients will be analysed at two time point...

Unguided Sacroiliac Injection: Effect on Refractory Buttock Pain in Patients With Spondyloarthropathies

This study is designed to evaluate the efficacy and safety of guide-free sacroiliac joint (SIJ) injection in refractory sacroiliac pain due to spondyloarthropathies.

TNFalfa Blocking Treatment of Spondylarthropathies

The purpose of the study is to establish a Danish cohort of spondylarthropathy (SpA) patients who are being treated with TNFalfa blockers. By following the TNFalfa blocking treated patient...

C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France

C.O.R.P.U.S. is the first French observatory of care practices in active inflammatory rheumatism of children and adults: rheumatoid arthritis, spondylarthropathy, and idiopathic juvenile a...

Medical and Biotech [MESH] Definitions

A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.

More From BioPortfolio on "Evaluation of Power Doppler US Technique for the Diagnosis of Spondylarthropathy"

Quick Search


Relevant Topic

Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Searches Linking to this Trial