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Effect of Different Dosing Regimens of Clopidogrel Before Elective Percutaneous Coronary Intervention (PCI) on Platelet Function

2014-08-27 03:30:01 | BioPortfolio

Summary

Adequate platelet inhibition before percutaneous coronary intervention (PCI) reduces peri-procedural and long-term ischemic complications. Documented reduced response to clopidogrel has been associated with subsequent major adverse cardiovascular events. Strategies to optimize platelet inhibition pre-PCI are under investigation.

This study sought to evaluate the effect on platelet aggregation of four different dosing regimens of clopidogrel given before elective PCI.

Study Design

Allocation: Randomized, Control: Dose Comparison, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Coronary Artery Disease

Intervention

Clopidogrel, Clopidogrel, Clopidogrel, Clopidogrel

Location

Hopital du Sacre-Coeur de Montreal
Montreal
Quebec
Canada
H4J 1C5

Status

Completed

Source

University of Montreal

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:30:01-0400

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