Rapid Sternal Closure System (TALON)

2014-08-27 03:32:06 | BioPortfolio


The primary objective is to establish if the Rapid Sternal Closure System improves early postoperative recovery as manifested by decreased pain and improved pulmonary function.

Secondary objectives include evaluation of Rapid Sternal Closure System with regard to SWCs (surgically treated sternal wound infection and sternal instability/non-union) as outlined in the protocol.

For a given study endpoint, the null hypothesis will be no difference between the RSCS group and the control group. The alternative hypothesis will be a difference between 2 groups. The statistical objective of this study is to reject the null hypothesis in favor of the alternative hypothesis.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention


Sternal Wound Infection


Rapid Sternal Closure System


Duke University Medical Center
North Carolina
United States




Duke University

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:32:06-0400

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A Simple Modification of the Conventional Figure-of-Eight Sternal Closure Technique.

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A Technique for 360-Degree Rigid Sternal Fixation with Sternal Plates and Wire Cerclage.

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Delayed Sternal Closure in Congenital Heart Surgery: A Risk-Benefit Analysis.

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Reconstruction of a deep sternal wound with exposed pericardium using an IMAP propeller flap: A case report.

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Medical and Biotech [MESH] Definitions

A syndrome which is characterized by symbrachydactyly and aplasia of the sternal head of pectoralis major.

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

Methods to repair breaks in tissue caused by trauma or to close surgical incisions.

A spasm of the diaphragm that causes a sudden inhalation followed by rapid closure of the glottis which produces a sound.

A method of stopping internal bleeding or blood flow, or the closure of a wound or body cavity, achieved by applying pressure or introducing an absorbent liquid, gel, or tampon.

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